General Hair Loss

What is alopecia ?what causes male to bald ?

Androgenic alopecia- also known as male pattern baldnss(MPB)  or androgenic alopecia  as name suggests  typically signifies  maturity onset pattern  in males  depending upon  ‘androgens’ related development , hair loss resulting in thinning is known as alopecia. When it is related to hormones (androgens) and genetics, it is known as androgenetic alopecia, or more commonly balding. Male pattern alopecia is characterised by a receding hairline and/or hair loss on the top and front of the head. Male pattern hair loss affects at least 50% of men at some point in their lives, and possibly as many as 80% by the age of 70 years. It affects different populations at different rates, probably because of genetics  Male pattern hair loss is more of a genetic and  hormonal related sequence , caused by a genetically determined sensitivity to the effects of dihydrotestosterone, or DHT in some areas of the scalp. DHT shorten the growth, or anagen, phase of the hair cycle, from a usual duration of 3-6 years to just weeks or months. This is  miniaturisation of the follicles, and producing progressively fewer and finer anagen hairs. The production of DHT is regulated by an enzyme called 5-alpha reductase.

 

Several genes are involved,with environmental factor at one hand and hormonal at other this accounts  for differing age of onset, progression, pattern and severity of hair loss in family members. The susceptibility genes are follows mendelian inheritance  from both mother and father. Most of the  time, genetic testing or prediction of potential ‘hair fall’will be meaning less and unreliable.

 

A few women present with male pattern hair loss because they have excessive levels of androgens as well as genetic predisposition. These women tend also to suffer from acne, irregular menses and excessive facial and body hair. These symptoms are characteristic of polycystic ovarian disease  (PCOS) although the majority of women with PCOS do not experience hair loss. Less often, congenital adrenal hyperplasia may be responsible. Females that are losing their hair with age are more likely to present with female pattern hair loss in which hormone tests are normal.